Thompson and Riden led Jacksonville in scoring with 14 points apiece, with 10 of Thompson's points coming in the second half.
He scored eight of the Tribe's 12 third-quarter points by himself.
“I knew that we needed a spark after we got down by 13 right after halftime and I took it upon myself to give it everything I had to help my team win,” Thompson said.
Jacksonville then moved into the lead, 48-47, on a Buckingham stick in that came with 1:17 to play.
The shot capped off a 6-0 Indian run and was the first time the Indians had led since the 2:27 mark of the first quarter.
Jacksonville expanded the lead to 50-47 with 30.8 seconds left when Londedric Taylor drained a pair of shots from the free throw line.
After John Tyler's Fred Ross added a couple of free throws with 22 ticks showing on the clock the Indian lead was cut to 50-49.
The Lions had one last opportunity to get the win, but an off-balanced shot from near the top of the key in the closing seconds by Keaunte Humber as the horn sounded fell short, just as the Lions' bid for victory did.
Buckingham earned a double-double (12 points, 14 rebounds) on the night and matched strides with the talented Lion post players all night, particularly in the fourth stanza when he went 4-of-4 from the field.
“This was a hard-fought win,” Buckingham said. “I think we got the best looks late and made our shots late and they (John Tyler) didn't.”
Jacksonville shot 72.7-percent (8-of-11) from the field in the fourth quarter, compared to the Lions hitting only 38.4-percent (5-of-13) from the field during the same time.”
Fred Ross led the Lions in scoring with 11 points and Tyus Bowser added 10 points and came up with a game-high 17 rebounds.